Wednesday, May 03, 2006
I have this 5-page cell biology paper to write, about E-cadherin/catenin and its role in breast cancer. Which is a rather reasonable deal, really. The subject is understandable, not too broad, and sufficiently interesting. (And if all else fails, I have Red Bull and hyperactive anime music.) But to my dismay, I find that the very nature of research gets in the way of a nice, comprehensive paper. Because independent studies sometimes agree with one another, which is convenient and a source of great relief to the struggling student, but more often than not they don't. One study suggests that adhesion = tumour suppression, another one shoots back that adhesion is neither necessary nor sufficient, and a bunch of others say that everything depends on the type of cancer, histological subtype, clonal selection in cell lines, and finally some clever bugger proposes a mechanism of action that is missing some crucial bits that no-one has any idea about, and so on. And then you are faced with the daunting prospect of reconciling a more than a decade's worth of mutually contradictory findings within a 5 page limit. You can't tie everything up with a nice neat bow - science is too messy for that. Of course, I still consider it a whole lot less messy than the humanities, but for now, I just wish the journal articles would bloody
agree on something.
Blast.
words were spilled on Wednesday, May 03, 2006